Protecting Life and Integrity in Research Act of 2025

This bill prohibits federal agencies from funding, supporting, or conducting research using human fetal tissue obtained from induced abortions. It allows federal research on tissue from miscarriages or stillbirths (defined as loss before 20 weeks or at 20+ weeks, respectively) and permits development of new cell lines not derived from abortion tissue. The bill amends the Public Health Service Act to restrict permissible tissue sources to miscarriage/stillbirth and revises definitions accordingly. It also repeals a prior provision allowing research on abortion-derived tissue and adds new restrictions on soliciting or accepting such tissue.