PASTEUR Act of 2026

The PASTEUR Act of 2026 creates a new government contracting program to incentivize development of new antimicrobial drugs for treating drug-resistant infections. The Health and Human Services Secretary would award contracts to pharmaceutical sponsors meeting specific criteria on clinical benefits, innovation, and public health impact, with annual payments ranging from $75 million to $300 million (adjusted for inflation). Contract requirements include ensuring drug availability, tracking resistance data, promoting appropriate use, and maintaining supply chains. The bill also establishes antimicrobial stewardship programs for hospitals and outpatient facilities and improves surveillance of antimicrobial use and resistance. This legislation aims to address antibiotic resistance by creating financial incentives for new treatments and improving how antimicrobials are used and monitored.