Gene Synthesis Safety and Security Act

This bill requires the U.S. Department of Health and Human Services to update safety guidelines for gene synthesis providers within one year of enactment. It mandates screening for dangerous DNA sequences, verifying customer identities, using approved software tools, and maintaining detailed records of orders and screening results. The law directly affects companies that synthesize custom DNA (like gene sequences for research or medicine), equipment manufacturers, and software developers in this field. Key provisions include creating a public list of "sequences of concern" for screening and providing technical assistance to help companies comply with the new requirements.