HR 1266 United States House · 119th Congress

Combating Illicit Xylazine Act

HR 1266, the Combating Illicit Xylazine Act, adds xylazine - a veterinary sedative increasingly found in illicit drug mixtures - to Schedule III of the Controlled Substances Act, regulating its use and trafficking. It directly affects veterinarians, animal owners, and manufacturers by allowing xylazine to be legally dispensed for animal use under specific veterinary prescriptions, while prohibiting non-veterinary human use. The bill includes transition periods (60 days for practitioners, 1 year for labeling) to ease compliance for manufacturers and practitioners, and requires the DEA and FDA to expedite necessary applications. It also mandates two congressional reports on xylazine's illicit use and trafficking patterns, and directs the Sentencing Commission to review penalties for offenses involving xylazine.
Bill status passed 3 of 5 stages cleared
Introduction
Feb 2025
Committee Review
Sep 2026
House Passage
Sep 2026
Senate Passage
President
Introduced Feb 12, 2025 Last action Sep 16, 2026
Maddy AI version diff · 1 comparison

What changed between versions

Introduced in House Engrossed in House · 3 edits · Sep 15, 2026
MINOR
The engrossed version of HR 1266 makes three main changes from the introduced version: it renumbers the xylazine definition paragraph in the Controlled Substances Act from (60) to (61), adds a new transition provision exempting existing xylazine manufacturers from Schedule III security capital expenditure requirements, and corrects references throughout from 'this title' to 'this Act.' The most substantive change is the new manufacturer relief provision, which eases the compliance burden on entities already producing xylazine at enactment.
REQUIREMENT

New subsection 4(b) provides that an entity manufacturing xylazine as of the date of enactment is not required to make capital expenditures to install Schedule III security standards for xylazine production. This gives existing manufacturers a transition period before they must meet the higher security requirements.

TECHNICAL

The paragraph number for the xylazine definition in section 102 of the Controlled Substances Act was renumbered from (60) to (61), likely reflecting that another substance was added to the definitions list between versions.

References throughout the bill were changed from 'this title' to 'this Act' in sections 1, 2(a), 4(f), and 6. This is a terminology correction since the legislation is an Act rather than a title of a larger statute.

Floor votes

How they voted

This bill passed the House by voice vote (no roll call recorded).
Full legislative history

Actions timeline

Total actions
18
Key actions
7
Committee
8
Amendments
2
Sep 15, 2026
Introduced
On motion to suspend the rules and pass the bill, as amended Agreed to by voice vote. (text: CR H5671-5672)
lower
Sep 15, 2026
Lower · Passed
Passed/agreed to in House: On motion to suspend the rules and pass the bill, as amended Agreed to by voice vote.
lower
Sep 15, 2026
Introduced
Mr. Guthrie moved to suspend the rules and pass the bill, as amended.
lower
Sep 14, 2026
Lower · Passed
Committee on the Judiciary discharged.
lower
Sep 14, 2026
Lower · Passed
Reported (Amended) by the Committee on Energy and Commerce. H. Rept. 119-816, Part I.
lower
Jul 21, 2026
Lower · Passed
Committee Consideration and Mark-up Session Held
lower
Jul 20, 2026
Lower · Passed
Committee Consideration and Mark-up Session Held
lower
Jun 25, 2026
Lower · Passed
Forwarded by Subcommittee to Full Committee by Voice Vote.
lower
Jun 25, 2026
Lower · Passed
Subcommittee Consideration and Mark-up Session Held
lower
Feb 12, 2025
Committee
Referred to the Subcommittee on Health.
lower
Feb 12, 2025
Committee
Referred to the Committee on Energy and Commerce, and in addition to the Committee on the Judiciary, for a period to be subsequently determined by the Speaker, in each case for consideration of such provisions as fall within the jurisdiction of the committee concerned.
lower
Feb 12, 2025
Introduced
Introduced in House
lower
1 primary · 114 co-sponsors

Sponsors

Role
Legislator
Party
State
District
P
Photo of Jimmy Panetta
Jimmy Panetta
DDemocratic
CA
19
Co
Photo of Adam Gray
Adam Gray
DDemocratic
CA
13
Co
Photo of Addison P. McDowell
Addison P. McDowell
RRepublican
NC
6
Co
Photo of Andrea Salinas
Andrea Salinas
DDemocratic
OR
6
Co
Photo of Andy Harris
Andy Harris
RRepublican
MD
1
Co
Photo of Angie Craig
Angie Craig
DDemocratic
MN
2
Co
Photo of August Pfluger
August Pfluger
RRepublican
TX
11
Co
Photo of Beth Van Duyne
Beth Van Duyne
RRepublican
TX
24
Co
Photo of Brad Finstad
Brad Finstad
RRepublican
MN
1
Co
Photo of Brad Knott
Brad Knott
RRepublican
NC
13
Co
Photo of Brian K. Fitzpatrick
Brian K. Fitzpatrick
RRepublican
PA
1