Modifies provisions relating to the prescriptive authority of advanced practice registered nurses

HB 327 expands prescribing authority for advanced practice registered nurses (APRNs) in Missouri. It allows APRNs (excluding nurse anesthetists) with special certification to prescribe Schedule III-V controlled substances and limited Schedule II drugs - specifically hydrocodone, hospice medications, and certain benzodiazepines/stimulants - under physician-supervised agreements. The bill restricts Schedule II prescriptions to a 120-hour supply without refills and prohibits APRNs from prescribing for themselves or family members. This directly affects APRNs and their collaborating physicians by broadening nurse-led care for common medications while maintaining safety limits. The changes replace outdated provisions to align with current nursing practice standards.